Withanolides -especially from Ashwagandha

Good morning!
Today I'm trying to find out all I can about Withanolides.
These are secondary metabolites found in plants of the nightshade family (Solanaceae) -same family as tomatoes...
So description so far:  28 carbon -steroidal backbones bound to lactones...
  Withaferin A

MANY of these out there.... well over 400!  Do all kinds of things -especially insect and herbicidal... Some have medicinal value.

Here's a neat site of some folks working on these!

Here's a full text pdf article on anticancer properties.... 


Cyclooxygenase-2 enzyme inhibitory withanolides from
Withania somnifera leaves