Wednesday, December 4, 2013

Hawthorn Extract: Herbal Strategy for Reducing High Blood Pressure





I won’t bore you with how bad high blood pressure (hypertension) is or how prevalent it is in the US.  I’ll give you the run down on the herb hawthorn (Crataegus oxycantha), and why it’s such a great component of any plan for reducing simple primary hypertension.  

I will state this though: If you are not a doctor, do not try to self medicate. Go see your naturopathic physician and work together to lower your blood pressure in a healthy way.  Also, if you are pregnant, don’t take this or any other herb/drug without first speaking to your health care provider.

Hawthorn is a Powerful Herb for Heart Health
Hawthorn (Crataegus oxycantha) is a small to medium-size thorny tree in the rose family (Rosaceae) with variations found throughout the more temperate regions of the world. Leaves, flowers, and fruit of hawthorn have been used in Native American and traditional European healing practices for over a thousand years.  In Australia, it’s considered to be an




All parts have been used to address

  • ·        Congestive heart failure
  • ·        Elevated cholesterol
  • ·        Anxiety


Hawthorn Extracts are Rich in Bioflavonoids
The prominent components of hawthorn with biological activity appear to be bioflavonoids.  These are complex three-ringed compounds with lots of variation (That’s a major generalization, but let’s just go with it!).  Bioflavonoids are created by plants to lend pigment to leaves and flowers.  In animals they often have pharmacological effects.  For the most part, though a great deal of substantiation exists, bioflavonoids have yet to intrude as a treatment option in the modern world of medicine. 



Vitexin


Flavonoid variations common in hawthorn species:

  • ·        vitexin-2-rhamnoside (flowers and leaves)
  • ·        hyperoside (aka. quercetin 3-galactoside), (berries)



These compounds work synergistically to reduce blood pressure in several ways.  The mechanisms include:

  • ·        Relaxation of vascular smooth muscle.  This decreases vascular resistance.
  • ·        Inhibit eicosanoid synthesis. These are compounds involved in the constriction of small blood vessels.
  • ·        Mild diuretic effect.  –they increase urinary flow.


Dosage Recommendations for Addressing Hypertension with Hawthorn Extracts
I've found that 500 mg of hawthorn (Crataegus spp) material standardized to 2% vitexin taken three times a day significantly reduces blood pressure.  Even better results may be experienced with the addition of magnesium (100-200 mg/day), Coenzyme Q10 (100 mg or more/day), and grape seed extract (50-100 mg/day)  

Here's a product by Jarrow Formulas I like (LINK) but there are plenty of other great choices...

Drug Interactions

  • ·        May have cumulative effect with diuretic drugs
  • ·        May enhance the action of digitalis


Adverse Effects Related to Hawthorn Extracts
Generally, hawthorn extracts are extremely safe.  While adverse effects are rare, the most common reported in literature are:

  • ·        Dizziness
  • ·        Headache
  • ·        Nausea
  • ·        Rash

Very large doses of hawthorn extract may possibly lead to drug induced hypotension, sedation, dizziness, vertigo, bradycardia, and respiratory depression. 

Hawthorn is Contraindicated in Pregnancy
Hawthorn should not be taken while pregnant since it may reduce the tone of the uterus. 


Helpful Resources
Albarouki E, Peterson A. Molecular and morphological characterization of Crataegus L. species (Rosaceae) in southern Syria. Botanical Journal of the Linnean Society. 2007

Chang WT, Dao J, Shao ZH. Hawthorn: Potential Roles in Cardiovascular Disease. Amer Jrnl Chin Med. 2005;33:1–10.

Daniele C, Mazzanti G, Pittler MH, Ernst E. Adverse-event profile of Crataegus spp.: a systematic review. Drug Saf. 2006;29:523–35.

Mills S, Bone K. London: Churchill Livingstone; 2000. Principles and Practice of Phytotherapy.


Here's a link to a Zipped collection of research papers I've found online. It's not conclusive, but hey, it's a start!   LINK to ZIPPED CRATAEGUS FILE

No comments:

Post a Comment